Tapentadol Prolonged Release for Managing Moderate to Severe, Chronic Malignant TumorRelated Pain
نویسندگان
چکیده
منابع مشابه
Tapentadol prolonged release for managing moderate to severe, chronic malignant tumor-related pain.
BACKGROUND Tapentadol prolonged release (PR) is effective and well tolerated for chronic osteoarthritis, low back, and diabetic peripheral neuropathic pain. OBJECTIVES To evaluate the efficacy and tolerability of tapentadol PR compared with placebo and morphine controlled release (CR) for managing moderate to severe chronic malignant tumor-related pain. STUDY DESIGN Randomized-withdrawal, p...
متن کاملDirect conversion from tramadol to tapentadol prolonged release for moderate to severe, chronic malignant tumour‐related pain
BACKGROUND A recent randomized-withdrawal, active- and placebo-controlled, double-blind phase 3 study showed that tapentadol prolonged release (PR) was effective and well tolerated for managing moderate to severe, chronic malignant tumour-related pain in patients who were opioid naive or dissatisfied with current treatment (Pain Physician, 2014, 17, 329-343). This post hoc, subgroup analysis ev...
متن کاملLasting Prolonged-Release Tapentadol for Moderate/Severe Non-Cancer Musculoskeletal Chronic Pain
INTRODUCTION Despite opioids' recognized role in the treatment of moderate/severe musculoskeletal chronic pain, their long-term benefits need investigation. We explored the lasting analgesic efficacy, tolerability, influence on life quality, and chronicity stage of the novel prolonged release (PR) opioid, tapentadol, in 30 outpatients. METHODS We evaluated patients' pain intensity and relief ...
متن کاملPractical considerations for the use of tapentadol prolonged release for the management of severe chronic pain.
PURPOSE Chronic pain is often challenging to address appropriately. Although patients with severe chronic pain may respond to treatment with an opioid analgesic, opioids are often associated with adverse effects that may lead patients to disrupt or discontinue therapy. In addition, opioid analgesics alone may not be effective for all types of chronic pain, including neuropathic pain. Tapentadol...
متن کاملTapentadol prolonged release for patients with multiple myeloma suffering from moderate-to-severe cancer pain due to bone disease
CONTEXT Myeloma bone disease (MBD) is a devastating complication of multiple myeloma that leads to severe pain. OBJECTIVES The aim of this study was to evaluate the efficacy and tolerability of tapentadol prolonged release (PR) in the management of patients with MBD suffering from moderate-to-severe cancer pain. METHODS A 12-week prospective study was carried out in 25 opioid-naïve MBD pati...
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ژورنال
عنوان ژورنال: July 2014
سال: 2014
ISSN: 2150-1149,1533-3159
DOI: 10.36076/ppj.2014/17/329